The FlexiGraft line of allografts are supported by pre-clinical and clinical publications which demonstrate the safety and efficacy of LifeNet Health allografts used in procedures such as ACL and PCL reconstruction.
- Tendons
Analysis of Graft Types Augmented With an Internal Brace for ACL Reconstruction: A Systematic Review.
Maginnis, C., Root, C., Schiavo, J. H., Ierulli, V. K., Vopat, B., & Mulcahey, M. K. (2024). The American Journal of Sports Medicine. https://doi.org/10.1177/03635465231196157Anterior Cruciate Ligament (ACL) Reconstruction Augmentation With Bone Marrow Aspirate, Demineralized Bone Matrix, and Suture Tape Demonstrates No Difference In Outcomes, But Faster Functional Recovery, Versus Non-augmented ACL Reconstruction.
Lavender, C. D., Schaver, A. L., Taylor, S., Peluso, R., Berdis, G., Singh, V., ... & Hewett, T. E. (2024). Arthroscopy: The Journal of Arthroscopic & Related Surgery. https://doi.org/10.1016/j.arthro.2024.06.042Donor age has no relevant role in biomechanical properties of allografts used in anterior cruciate ligament (ACL) reconstruction: A systematic review.
Grassi, A., Agostinone, P., Di Paolo, S., Altovino, E., Gallese, A., Akbaba, D., ... & Zaffagnini, S. (2024). Knee Surgery, Sports Traumatology, Arthroscopy, 32(5), 1123-1142. DOI: 10.1002/ksa.12113Remnant Preservation of the Primary Vertical Graft in Revision Anterior Cruciate Ligament Reconstruction.. Ahn J-H, Son D-W, Ahn J-H, Park D-W, Park J-H. Marshall Journal of Medicine, 9(3), 3.
Return to activity following ACL Reconstruction with the Fertilized ACL: A retrospective study. . Mirzayan, R., & Mills, E. S. (2021). Arthroscopy Techniques, 10(8), e1935-e1941.
Chronic distal biceps tendon tear reconstruction with tibialis anterior allograft. Lavender, C., Hewett, T., Johnson, J., Peluso, R., Patel, T., & Taylor, S. (2023). Arthroscopy Techniques, 10(8), e1935-e1941.
Better Radiographic Reduction and Lower Complication Rates With Combined Coracoclavicular and Acromioclavicular Ligament Reconstruction Than With Isolated Coracoclavicular Reconstruction. Walters, J. D., Ignozzi, A., Bustos, F., Werner, B. C., & Brockmeier, S. F. (2021). Arthroscopy, sports medicine, and rehabilitation, 3(2), e441-e448.
Anatomic reconstruction of the anterior cruciate ligament of the knee with or without reconstruction of the anterolateral ligament: A meta-analysis. Yin J, Yang K, Zheng D, Xu N. J Orthop Surg (Hong Kong). 2021 Jan-Apr;29(1):2309499020985195.
Revision Risk After Allograft Anterior Cruciate Ligament Reconstruction: Association With Graft Processing Techniques, Patient Characteristics, and Graft Type. Tejwani SG, Chen J, Funahashi TT, Love R, Maletis GB. Am J Sports Med. 2015 Nov;43(11):2696-705.
The effect of donor age and low-dose gamma irradiation on the initial biomechanical properties of human tibialis tendon allografts. Greaves LL, Hecker AT, Brown CH Jr. Am J Sports Med. 2008;36(7):1358-66.
Effect of Donor Age on Patellar Tendon Allograft ACL Reconstruction. Hampton DM, Lamb J, Klimkiewicz JJ. Orthopedics. 2012; Vol 35, Issue 8: e1173-31176.
Distal biceps reconstruction 13 years post-injury. Burrus MT, Chhabra AB. Ther Adv Musculoskelet Dis. 2015 Apr;7(2):56-9.
All-Inside Posterior Cruciate Ligament Reconstruction With a GraftLink. Adler GG. Arthrosc Tech. 2013 Mar 29;2(2):e111-5. doi: 10.1016/j.eats.2012.12.004.
Tibial fixation of anterior cruciate ligament allograft tendons: comparison of 1-, 2-, and 4-stranded constructs. Park DK, Fogel HA, Bhatia S, Bach BR Jr, Gupta A, Shewman EF, Wang V, Verma N, Provencher MT. Am J Sports Med. 2009 Aug;37(8):1531-8.
Does irradiation affect the clinical outcome of patellar tendon allograft ACL reconstruction? Rihn JA, Irrgang JJ, Chhabra A, Fu FH, Harner CD. Knee Surg Sports Traumatol Arthrosc. 2006 Sep;14(9):885-96.
Comparison of human tendon allografts and autograft used in knee reconstruction. Klimkiewicz JJ, Samsell BJ, Riff A, DeBerardino TM, Moore MA. Current Orthopaedic Practice. 2011;22(6): 494-502.
A retrospective comparison of the incidence of bacterial infection following anterior cruciate ligament reconstruction with autograft versus allograft. Katz LM, Battaglia TC, Patino P, Reichmann W, Hunter DJ, Richmond JC. Arthroscopy. 2008 Dec;24(12):1330-5.
Surgical management of knee dislocations. Chhabra A, Cha PS, Rihn JA, Cole B, Bennett CH, Waltrip RL, Harner CD. Surgical technique. J Bone Joint Surg Am. 2005 Mar;87 Suppl 1(Pt 1):1-21.
Histologic findings of anterior cruciate ligament reconstruction with Achilles allograft. Chun CH, Han HJ, Lee BC, Kim DC, Yang JH. Clin Orthop Relat Res. 2004 Apr;(421):273-6.
Posterolateral corner reconstruction of the knee: surgical technique utilizing a bifid Achilles tendon allograft and a double femoral tunnel. Sekiya JK, Kurtz CA. Arthroscopy. 2005 Nov;21(11):1400.
Transtibial and tibial inlay double-bundle posterior cruciate ligament reconstruction: Surgical technique using a bifid bone-patellar tendon-bone allograft. Sekiya JK, Kurtz CA, Carr DR. Arthroscopy. 2004 Dec;20(10):1095-100.
An allograft salvage technique for failure of the Darrach procedure: a report of four cases. Sotereanos DG, Göbel F, Vardakas DG, Sarris I. J Hand Surg Br. 2002 Aug;27(4):317-21.
Results of anatomic lateral ankle ligament reconstruction with tendon allograft. Ellis SJ, Williams BR, Pavlov H, Deland J. HSS J. 2011 Jul;7(2):134-40.
Change in Size of Hamstring Grafts During Preparation for ACL Reconstruction: Effect of Tension and Circumferential Compression on Graft Diameter. Cruz AI Jr, Fabricant PD, Seeley MA, Ganley TJ, Lawrence JT. J Bone Joint Surg Am. 2016 Mar 16;98(6):484-9.
Impact of Hamstring Graft Diameter on Tendon Strength: A Biomechanical Study. Boniello MR, Schwingler PM, Bonner JM, Robinson SP, Cotter A, Bonner KF. Arthroscopy. 2015 Jun;31(6):1084-90.
Use of controlled low dose gamma irradiation to sterilize allograft tendons for ACL reconstructions: biomechanical and clinical perspective. Samsell BJ, Moore MA. Cell Tissue Bank. 2012; 13(2): 217-223.
Inactivation of enveloped and non-enveloped viruses on seeded human tissues by gamma irradiation. Moore MA. Cell Tissue Bank. 2012 Aug;13(3):401-7.
Effect of low dose and moderate dose gamma irradiation on the mechanical properties of bone and soft tissue allografts. Balsly CR, Cotter AT, Williams LA, Gaskins BD, Moore MA, Wolfinbarger L Jr. Cell Tissue Bank. 2008 Dec;9(4):289-98.
- Dowels
Two-Stage Revision Anterior Cruciate Ligament Reconstruction with Cannulated Allograft Bone Dowels Soaked in Bone Marrow Aspirate Concentrate. Fortier, L. M., Gursoy, S., Singh, H., & Chahla, J. (2021). Arthroscopy techniques, 10(12), e2699-e2708.
Allograft Bone Dowel Incorporation to Tibial and Femoral Tunnels in Two-Stage Revision Anterior Cruciate Ligament Reconstruction. Buyukdogan K, Laidlaw MS, Kew ME, Miller MD. Arthroscopy: The Journal of Arthroscopic & Related Surgery. 2021. In press.
Two-Stage Anterior Cruciate Ligament Reconstruction Revision Surgery for Severe Bone Defects With Anterolateral Ligament Reconstruction Technique. Maestro Fernández A, Pipa Muñiz I, Rodríguez García N. Arthrosc Tech. 2020 Feb 7;9(3):e327-e337.
Two-Stage Revision Anterior Cruciate Ligament Reconstruction Using Allograft Bone Dowels. Buyukdogan K, Laidlaw MS, Miller MD. Arthrosc Tech. 2017 Aug 14;6(4):e1297-e1302.
Revision Anterior Cruciate Ligament Reconstruction: Results of a Single-stage Approach Using Allograft Dowel Bone Grafting for Femoral Defects. Werner BC, Gilmore CJ, Hamann JC, Gaskin CM, Carroll JJ, Hart JM, Miller MD. J Am Acad Orthop Surg. 2016 Aug;24(8):581-7.