Dermacell Porous Product Specifications

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Instructions for Use
Product Specifications

Dermacell®  Porous 
Acellular Dermal Matrix

Dermacell® Porous is a thin yet robust, naturally porous, advanced human acellular dermal matrix, decellularized using Matracell® technology. It is designed as a non-sided graft for easy handling and application that is ready-to-use out of the package and shelf-stable for room temperature shipping and storage.

  • Thin ADM: Faster full incorporation with enhanced vascularization and cell infiltration.1
  • Intact Dermal Structure: Retains endogenous growth factors and types of collagen in native human dermis.2,3
  • Naturally Porous: A naturally porous structure with the basement membrane removed to support drainage.4
  • Reticular Only: No side orientation for easy application.
  • Easy Handling: Suturable and easy to handle, place and re-position.
  • Safe and Convenient: Terminally sterile to a medical device-grade sterility assurance level (SAL) of 10-6, room temperature storage, and ease of application – no need to thaw, rinse or pre-hydrate.5,6
  • Biohospitable: Intact human extracellular matrix decellularized to remove cells and ≥97% of DNA minimizing inflammatory potential and immune response.7
Clinical Application
  • Chronic wounds such as diabetic foot ulcers (DFUs), venous stasis ulcers (VSUs), arterial ulcers, pressure ulcers, dehisced surgical wounds, and traumatic burns.
  • Dermacell Porous can be placed over exposed tendon, bone, joint capsule, and muscle.
Order CodeDescriptionSizing
DP-03Naturally Porous1.8 cm x 1.8 cm (0.2 – 0.5 mm)
DP-06Naturally Porous2 cm x 3 cm (0.2 – 0.5 mm)
DP-12Naturally Porous3 cm x 4 cm (0.2 – 0.5 mm)
DP-25Naturally Porous5 cm x 5 cm (0.2 – 0.5 mm)
DP-42Naturally Porous6 cm x 7 cm (0.2 – 0.5 mm)
References
  1. LifeNet Health, TR ED-23-0306, In vivo Assessment of Local Tissue Response and Cell Infiltration – Animal study results may not be predictive of clinical results.
  2. Agrawal H, Tholpady SS, Capito AE, Drake DB, Katz AJ. Macrophage phenotypes correspond with remodeling outcomes of various acellular dermal matrices. Open Journal of Regenerative Medicine. 2012; 01(03):51-59. https://doi.org/10.4236/ojrm.2012.13008
  3. 68-20-047, Analysis of the Acellular Matrix, Growth Factors, and Cytokines Present in Oracell.
  4. LifeNet Health, ED-22-038, Cytotoxicity Extraction Buffer Volume Comparison for Varying Thicknesses of Dermis.
  5. Moore MA, Samsell B, McLean J. Allograft Tissue Safety and Technology. In: Biologics in Orthopaedic Surgery.2019:49-62. https://doi.org/10.1016/b978-0-323-55140-3.00005-9
  6. Zenn MR, Salzberg CA. A direct comparison of Alloderm-Ready to Use (RTU) and Dermacell in immediate breast implant reconstruction. Eplasty. 2016;16:e23.
  7. Moore MA, Samsell B, Wallis G, et al. Decellularization of human dermis using non-denaturing anionic detergent and endonuclease: a review. Cell Tissue Bank. 2015; 16(2):249-259. https://doi.org/10.1007/s10561-014-9467-4