CONVENIENCE OF AMBIENT STORAGE

WHAT IT DOES

Preservon is a patented technology that enables room-temperature storage of fully-hydrated and ready-to-use grafts, providing unsurpassed convenience and reliability compared with traditional preservation methods. Preservon technology provides fully-hydrated grafts without freezing, and ambient temperature storage without compromising the graft's native biomechanical and biochemical properties. Additionally, Preservon-treated grafts are ready to use out of the package in as little as 30 seconds, eliminating lengthy thawing or rehydration procedures and saving valuable operating room time.

WHY IT'S NEEDED 

Traditional frozen or freeze-dried grafts impose numerous challenges that Preservon resolves. Frozen grafts must be shipped on dry ice and stored in specialized, monitored freezers. Freeze-dried grafts can be shipped and stored at ambient temperatures, but the lyophilization process can damage some types of tissue. Both of these preservation methods can require up to 60 minutes of valuable operating room time for thawing or rehydration. 

WHY IT'S DIFFERENT 

HOW IT WORKS

Preservon-treated grafts are immersed in a proprietary glycerol-based solution and then centrifuged to remove excess.

Glycerol is a non-toxic, odorless, colorless, and biodegradable liquid used in a wide variety of applications worldwide, from cosmetics and food, to pharmaceuticals and medical devices.

The glycerol molecules displace free-standing water molecules within the graft and act as a humectant to maintain the graft's moisture.

Peer-Reviewed Publications

Samsell B, Softic D, Qin X, McLean J, Sohoni P, Gonzales K, Moore MA. Preservation of allograft bone using a glycerol solution: a compilation of original preclinical research. Biomater Res. 2019 Feb 13;23:5. doi: 10.1186/s40824-019-0154-1

Rodway I, Gander J. Comparison of Fusion Rates between Glycerol-Preserved and Frozen Composite Allografts in Cervical Fusion. Int Sch Res Notices. 2014 Oct 28;2014:960142. doi: 10.1155/2014/960142

Graham RS, Samsell BJ, Proffer A, Moore MA, Vega RA, Stary JM, Mathern B. Evaluation of glycerol-preserved bone allografts in cervical spine fusion: a prospective, randomized controlled trial. J Neurosurg Spine. 2015 Jan;22(1):1-10. doi: 10.3171/2014.9.SPINE131005

Bertasi G, Cole W, Samsell B, Qin X, Moore M. Biological incorporation of human acellular dermal matrix used in Achilles tendon repair. Cell Tissue Bank. 2017 Sep;18(3):403-411. doi: 10.1007/s10561-017-9628-3