Complete portfolio of structural spine allografts

Our cervical, thoracic, and lumbar allograft interbody and corpectomy spacers are clinically proven in more applications than any other allograft spine implant provider. As a result, we are the world's most trusted provider of transplant solutions.

• Proven strength and efficacy — with higher fusion rate v. PEEK
• Designed to work with DePuy Synthes instrumentation
• Distributed by DePuy Synthes

VertiGraft Allograft Reference Guide

Better Outcomes

Structural allografts provide better outcomes
than PEEK cages in spinal fusion procedures.
– Patients treated with structural allografts had a 90.5% pooled fusion rate, were 61% less likely to have pseudarthrosis and had a 4.68-fold higher likelihood of fusion than those with PEEK cages.¹

5-Fold Lower Risk Lower of
Pseudarthrosis in 1-Level ACDF²
–52% of patients with PEEK implants had radiographic pseudarthrosis, compared to only 10% of those with structural allografts. Of those with pseudarthrosis, only 1 patient with a structural allograft (14%) required revision surgery, compared to 7 patients in the PEEK group (24%), with no significant differences between patient demographics. ²

Nearly 7-Fold Lower Risk Lower of
Pseudarthrosis in Multi-Level ACDF³
–74% of patients with PEEK implants had radiographic pseudarthrosis compared to 11% of those with structural allografts. Of those with pseudarthrosis, 5 patients with a PEEK implant (14%) required revision surgery, compared to 0 patients in the structural allograft cohort. Additionally, structural allografts extend previous findings from single-level ACDF:¹ — further supporting use of structural allografts in cervical fusion procedures.³

Dr. Michael Haglund shares his experience using VertiGraft allografts.

He depends on these high-quality  allografts to help his patients heal. Dr. Haglund discusses how he is better able to assess fusion with allografts than with synthetic implants, and nods to the advantage of not having a second site morbidity of an autograft. 

References:

1. Nida Fatima, Elie Massaad, Ganesh M. Shankar, John H. Shin, Structural Allograft versus Polyetheretherketone Implants in Patients Undergoing Spinal Fusion Surgery: A Systematic Review and Meta-Analysis, World Neurosurgery, Volume 136, 2020, Pages 101-109, ISSN 1878-8750, https://doi.org/10.1016/j.wneu.2020.01.006.
2. Krause KL, Obayashi JT, Bridges KJ, Raslan AM, Than KD. Five-fold higher rate of pseudarthrosis with polyetheretherketone interbody device than with structural allograft used for 1-level anterior cervical discectomy and fusion. J Neurosurg Spine 2019;30:46-51.
3. Teton ZE, Cheaney B, Obayashi JT, Than KD. PEEK interbody devices for multilevel anterior cervical discectomy and fusion: association with more than 6-fold higher rates of pseudarthrosis compared to structural allograft. J Neurosurg Spine. 2020 Jan 24:1-7. Doi: 10.3171/2019.11.SPINE19788. Epub ahead of print. PMID: 31978889.